Xi'an Sengmei Biological Technology Co., Ltd
Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
Xi'an Sengmei Biological Technology Co., Ltd
We are professional supplier of animal and plant extracts.
Xi'an Sengmei Biological Technology Co., Ltd
We are professional supplier of animal and plant extracts.
Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
Description
Superlist Name:Quetiapine fumarate
Molecular Formula:2(C21H25N3O2S).C4H4O4
CAS No.:111974-72-2
Purity:99%
Synonyms:2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate
Molecular Weight:883.09
Appearance:White powder
Introduction
Quetiapine is an atypical antipsychotic approved for the treatment of schizophrenia, bipolar disorder, and as an add-on to treat depression.
COA
Items of test | As per Company Standard WS1-(x-133)-2003Z & ZLBZ-E023-3 | Result
|
Characters | Appearance: White or pale yellow crystalline powder, odorless and tasteless. | Complies
|
Solubility : Freely soluble in glacial acetic acid; slightly soluble in methanol or ethanol; practically insoluble in water. | Complies
| |
Identification
| A Reaction with KMnO4 TS produces brown precipitate. | Complies
|
B Light absorption has maximum at 289±1nm. | Complies
| |
C IR spectrum is concordance with the reference One. | Complies
| |
D Melting point: 172-176°C with melting range≤4°C | 173.5-174.0°C
| |
pHValue | 0.01g/ml solution,5.0-6.0 | 5.6
|
Related Substances (HPLC)
| Any impurity ≤0.10% | < 0.10%
|
Total of all impurities ≤0.20% | <0.20%
| |
Loss on drying | ≤0.5% | 0.1%
|
Residue on Ignition | ≤0.1% | <0.1%
|
Chloride | ≤140ppm | < 140ppm
|
Heavy metals | ≤10ppm | <10ppm
|
Assay | Not less than 99.0% |
99.7% |