Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
6/10
Xi'an Sengmei Biological Technology Co., Ltd
We are professional supplier of animal and plant extracts.
Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
6/10
Introduction:
Product Name: chloramphenicol | Appearance : White or slightly yellowish white fine crystalline powder or needles |
Cas No.: 56-75-7 | Form: White or slightly yellowish white |
Purity: >99% | 323.1294 |
MF: C11H12Cl2N2O5 | Brand: HUISUN |
package: 25kg/fiber can or as per your request |
Specification:
Test Item | Analysis Specification | Result |
Description | Fine white or grayish white or yellowish white needle-like crystals or Elongated plates | yellowish white needle-like crystals or Elongated plates |
Identification | positive | postitive |
Melting point | 149 ~ 153°C | 149.0~ 152.30°C |
Assay | 98.5 ~ 102% | 99.0% |
Loss on drying | ≤0.5% | 0.0012 |
Residue on ignition | ≤0.1% | 0.0009 |
PH | 5.0 ~ 7.5 | 5.68 |
Specific rotation | +18.5 ~ +20 ° | +18.8° |
Heavy metals | ≤0.001% | <0.001% |
Related substances | The any secondary spot ≤0.5% | <0.5% |
total≤2% | Total <2% | |
Chloride | ≤0.005% | <0.005% |
Crystallinity | Meets the requirements | Meets the requirements requiremenrequirements |
Function&Application:
Chloramphenicol
is effective against a wide variety of Gram-positive and Gram-negative
bacteria, including most anaerobic organisms. Due to resistance and
safety concerns, it is no longer a first-line agent for any indication
in developed nations, although it is sometimes used topically for eye
infections; nevertheless, the global problem of advancing bacterial
resistance to newer drugs has led to renewed interest in its use. In
low-income countries, chloramphenicol is still widely used because it is
exceedingly inexpensive and readily available.
The
most serious adverse effect associated with chloramphenicol treatment
is bone marrow toxicity, which may occur in two distinct forms: bone
marrow suppression, which is a direct toxic effect of the drug and is
usually reversible, and a plastic anemia, which is idiosyncratic (rare,
unpredictable, and unrelated to dose) and generally fatal.