China supplier new products Reserpine

  • Purchase Qty: 1
  • Unit: Kg(s)
  • Fob Unit Price: US $50
  • Production Capacity:300kg/month
  • Payment Terms:T/T
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Xi'an Sengmei Biological Technology Co., Ltd

Business Type:Manufacturer

Country/Region:China

Ddu Verified

HOT Rank

6/10

Product Information

  • Active Ingredients:Reserpine
  • Chemical Formula:C33H40N2O9
  • Molecular Weight:608.68
  • Assay:99%
  • Pharmacopeia:CP
  • Package Type:Drum&plastic bags or Aluminum
  • Shelf Life:2 years
  • Storage:Sealed
  • Place of Origin:XI'AN CHINA
  • CAS:50-55-5

Description

Introduction

Name: Reserpine

Cas No.:  50-55-5

Apperance: White fine powder

Purity: 8%,20%,40%,98%,4:1, 5:1 ,10:1

Molecular weight:608.68 

Molecular formula: C33H40N2O9 

 

 

Reserpine was blocked by adrenergic neurons of antihypertensive drugs.This product is the depletion of peripheral sympathetic nerve endings of adrenaline, heart, brain and other tissues of catecholamines and 5 - HT to anti-high blood pressure, slow heart rate and inhibition of the central nervous system. Antihypertensive effect primarily by reducing cardiac output and reduced peripheral resistance, part of the cardiovascular reflex inhibition to achieve.Reserpine acts on hypothalamic area produce sedation, but no cause drowsiness and anesthetic effects, does not change the sleep EEG, can ease the anxiety of patients with hypertension, tension and headaches.Experimental animal for less than the clinical dose of reserpine, which appears miosis, eyelid wrinkles and sagging, hypothermia, gastrointestinal symptoms such as the acceleration of activity. 


Function

Reserpine can lower blood pressure and heart rate, the role of slow, moderate and long-lasting stability and the role of the central nervous system, is a good sedative. The treatment of hypertensive patients using reserpine patch topical Lee, Shen buck stickers, hanging pressure attached to external use Chinese medicine posted combined to strengthen the blood pressure lowering effect. 
  • Reserpine was blocked by adrenergic neurons of antihypertensive drugs.
  • Reserpine is the depletion of peripheral sympathetic nerve endings of adrenaline, heart, brain and other tissures of catecholamines and 5-HT to anti-high blood pressure, slow heart rate and inhibition of the central nervous system.
  • Reserpine acts n hypothalamic area produce sedation, but no cause dorwsiness and anesthetic effects, does not change the sleep EEG, can ease the anxiety of patients with hypertension, tension and headaches.
  • Expermental animal for less than the clinical dose of reserpine, which appears miossi, eyelid wrinkles and sagging, hypothermia, gastrointestinal symptoms such as the acceleration of activity.

Application


  • Applied in the food filed, it has become a new raw material which used in food and beverage industry
  • Applied in the health product field, which is a natural health product to regulate sleeping
  • Applied in the pharmaceutical field, with the good effect of treating hepatitis

Sepcification

 

Items

Requirements

Results


Description


Appearance  

A off white crystalline powder, odor, apricot smell, tasteless

Conforms


Solubility

freely soluble in chloroform, sparingly soluble in acetone, and practically insoluble in water, methanol, ethanol or ether. 

Conforms

 


Specific optical rotation

-115~-131°

-128.4°


Identification


Color reaction

A yellow color is produced, 5 minutes into the blue

Conforms


Color reaction

A rose red color is produced after 2 minutes



Color reaction

A blue color is produced

Conforms


IR

Infrared absorption spectra of test and standard(or infrared reference spectra No. 195) are concordant

Conforms

 


Tests


Oxidation products

According to the UV Visible spectrophotometry, the 0.2mg/ml sample acetic acid solution absorbance was measured at a wavelength of 338nm not more than 0.10

Conforms


Related Substances (HPLC)

Total Impurities ≤1.5%

1.46%


Loss on drying

≤0.5%

0.31%


Residue on ignition

≤ 0.15%

0.09%


Assay(On dried basis)

98.0% ~102.0%(HPLC) 

99.2%


 

 





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